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The 500 mg blend

What Is the Melonex Proprietary Blend, and Why Are the Amounts Hidden?

Quick answer

The Melonex proprietary blend is one 500 mg line on the label that groups three amino acid forms. US rules let a company print the blend total and skip each amount, but the names must run from heaviest to lightest. That order caps the second name at 250 mg and the third at 167 mg.

Written by the Melonex label deskUpdated

The basics01

What is a proprietary blend in a supplement?

A proprietary blend is a group of ingredients printed on a Supplement Facts panel as one line with one combined weight.

The rule behind it is 21 CFR 101.36. The blend gets a name, and the ingredients inside it are listed in descending order of predominance by weight. The weight printed for the blend is the combined weight of all of them, so individual amounts need not be shown (21 CFR 101.36, Supplement Facts).

The word "Proprietary Blend" is the label's own. A company may keep a recipe private. A buyer, in return, cannot see how the weight is split.

That is a lawful way to print a label. It is also a limit on what you can check.

The Melonex Supplement Facts panel showing the Proprietary Blend 500 mg line
The blend line on the bottle: one total, three names, no amounts

On the bottle02

What is in the Melonex proprietary blend?

The Melonex proprietary blend is 500 mg per capsule and names L-Citrulline DL-Malate, L-Arginine (Alpha-Ketoglutarate dihydrate) and L-Arginine HCL, in that order.

Serving size is 1 capsule and a bottle holds 60 servings. The Daily Value is not established. The label prints no figure for any of the three names.

The front of the bottle says "Advanced Support" and carries three starred lines. The star leads to the FDA statement, which says the claims have not been evaluated. See the supplement facts page for the full panel.

  1. 1L- Citrulline dl - Malate167 mg or more of the 500 mg blend
  2. 2L-Arginine (Alpha-Ketoglutarate dihydrate)under 250 mg of the 500 mg blend
  3. 3L - Arginine HCLunder 167 mg of the 500 mg blend

From the Supplement Facts panel, in label order. The label prints 500 mg for the whole Proprietary Blend and no amount for any name, so the limits shown come from the order alone. Other ingredients (hydroxypropyl methylcellulose capsule, microcrystalline cellulose, magnesium stearate) are not part of the blend.

Label order03

How much of each ingredient can the Melonex blend hold?

The Melonex label order means the first name is at least 167 mg, the second is at most 250 mg and the third is at most 167 mg.

Work it through. Three names share 500 mg. The first is the heaviest, so it must weigh more than the others, and at least a third of the total: 500 divided by 3 is about 167 mg. It can be nearly 500 mg.

The second name cannot outweigh the first. If both were equal they would each be 250 mg, so 250 mg is the most the second can be. The third cannot outweigh the second, and that caps it at 167 mg.

500 mgone Proprietary Blend per capsule, amounts of the three names not printed

Proprietary Blend 500 mg
  1. L-Citrulline DL-Malate167 to 500 mg
  2. L-Arginine alpha-ketoglutarateup to 250 mg
  3. L-Arginine HClup to 167 mg

Bars show the widest range the label order allows for each name (21 CFR 101.36, Supplement Facts). The real split is not printed.

These are weights of salt forms. The malate, alpha-ketoglutarate and hydrochloride parts add weight, so the amino acid itself weighs less. The ranges are arithmetic, not measured amounts.

Blend vs studies04

Does a 500 mg blend match the doses used in studies?

No. Studies of these amino acids use grams a day, and one Melonex capsule holds half a gram of blend in all.

Citrulline studies summarized by Cleveland Clinic ran 3 to 8 g a day for 1 to 16 weeks (Cleveland Clinic, L-citrulline). A sports trial of arginine alpha-ketoglutarate gave 4 g per dose, 12 g a day, to 35 men (Campbell 2006, L-arginine AKG trial). Pooled arginine trials mostly used several grams a day, with no further change above 9 g a day (Shiraseb 2022, arginine and BP).

At the label limit of two capsules the blend is 1 g. Even if all of it were one ingredient, it would sit below those studies.

  • L-Citrulline DL-Malate

    At most 16.7% of the low study amount
    Most one Melonex capsule can hold (label order)500 mg
    3 to 8 g a day of citrulline, 1 to 16 weeks (Cleveland Clinic summary)3,000-8,000 mg

    The label prints no amount for this name; 500 mg is the ceiling its place in the list allows. (Cleveland Clinic, L-citrulline)

  • L-Arginine alpha-ketoglutarate

    At most 6.2% of the low study amount
    Most one Melonex capsule can hold (label order)250 mg
    4 g per dose, 12 g a day, in a 35-man sports trial4,000-12,000 mg

    The label prints no amount for this name; 250 mg is the ceiling its place in the list allows. (Campbell 2006, L-arginine AKG trial)

Red bars: the most one daily capsule can hold of that name, worked out from the label order (the real amount is not printed). Green bars: the amount used in the study we found, set to full width. A studied dose says what was tested, not what works for you, and no study tested Melonex.

This is a size comparison, not a verdict. A study dose shows what was tested. It does not tell you what works for you.

The trade-off05

Why do supplement makers use proprietary blends?

Makers use blends to keep a recipe private and to keep the label short. Buyers pay for that with less information.

What a blend line gives and takes away
For the makerFor the buyer
A private recipeNo amount printed for each name
A short one-line panelNo way to compare with a study dose
One serving covers several ingredientsOnly the label order hints at the split

The label order does give a partial view. In Melonex, citrulline malate must lead. That fits a formula built around citrulline, but the label does not confirm how big the lead is.

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How to judge06

How do you judge any proprietary blend supplement?

Judge a proprietary blend supplement by five checks: total weight, name order, salt forms, studied doses and published testing.

  1. Read the total

    Compare the blend weight with the grams used in studies.

  2. Read the order

    Work out the floor for the first name and the ceilings for the rest.

  3. Spot the salts

    Words like malate, HCl or alpha-ketoglutarate add weight that is not the active part.

  4. Ask for testing

    No lab report for Melonex is published. Lot M-26/ME-2606 and CoA M-2606-26-ME are seller references, not lab proof.

Before you buy07

Is the Melonex blend safe with medicines?

Arginine can add to blood-pressure medicines, so ask your doctor or pharmacist first.

Mayo Clinic, MSK and Cleveland Clinic advise against arginine after a recent heart attack (Mayo Clinic, L-arginine) (MSK, Arginine) (Cleveland Clinic, L-arginine). Keep taking your prescribed medicine (AHA, Managing BP Medications). Chest pain or trouble breathing means 911.

Bottom line08

Should the hidden amounts change your decision?

They should at least slow it down. You cannot judge a dose you cannot see.

The sales page describes "targeted nutritional support for heart health, healthy blood pressure, and overall cardiovascular wellness" and cites no studies (Melonex sales page). No source tests Melonex. NCCIH says no dietary supplement has been shown to work like blood-pressure drugs (NCCIH, Hypertension).

If you still want to try it, a 60-day money-back guarantee is described for Melonex; confirm the live policy at checkout. Read does Melonex work first.

Melonex: from $49 a bottle60 capsules · 2, 3 or 6 bottles · free US shipping on 3 and 6 · 60-day money-back guarantee

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FAQ09

Melonex proprietary blend questions

Why doesn't Melonex list the amount of each ingredient?

US labeling rules let a company print one combined weight for a proprietary blend and skip the individual amounts, as long as the names are listed in descending order by weight. Melonex uses that option for its 500 mg blend.

Is a proprietary blend bad?

Not by itself. A blend is a lawful label format. The drawback is that you cannot see each amount or compare it with a study dose, so you must judge the product by the total and the name order.

Can I work out how much citrulline is in a Melonex capsule?

Only as a range. Citrulline malate is listed first, so it is at least 167 mg of the 500 mg blend. The malate part adds weight, so the citrulline itself is less. No exact figure is printed.

Is 500 mg of a blend a lot for a supplement?

It is small next to study doses. Citrulline studies used 3 to 8 g a day, and one arginine alpha-ketoglutarate trial used 12 g a day. One Melonex capsule is 0.5 g of blend, split across three names.

Does the FDA require blend amounts on the label?

No. Under 21 CFR 101.36 a blend shows its combined weight, and members are listed in descending order of predominance by weight. Individual amounts need not be shown. The FDA does not approve supplements before sale.

How can I ask the company for the Melonex amounts?

Call the order desk at +1 (855) 889-3137, or write to the distributor named on the label, Instituto Experience of Lakeland, FL. We have not seen any published amounts, so treat any figure as unconfirmed until it is in writing.

Who wrote this10

Written and reviewed by

Written byThe Melonex label deskMelonexcardio, Official U.S. Melonex shop

Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.

Medically reviewed byDr. Maria Menucci, MD, PhysicianRole: Medical reviewerReview date: October 19, 2026

Last updated . See our editorial standards and how we check reviews. This website is the information site for the Official U.S. Melonex shop. It is not the manufacturer or the distributor named on the label. We make money when you buy through our order links.

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